TOPICAL DERMATOLOGICAL


GERSITOL®

GERSITOL A.G.E. LOTION

Dermal lotion with Essential Fatty Acids and Vitamin A

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GERSITOL ZINC CREAM

Protective cream with
Zinc Oxyde and Vitamin A

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HIDROBAS®

HIDROBAS DRESSING

Antiseptic dressing on hydrosoluble base

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PROPÓLEO-D®

Propóleo-D® products line has stabilized Propolis as its active ingredient.

Propolis pharmaceutical properties that support its therapeutic or prophylactic use are linked to its content of polyfenols: flavonoids, aromatic acids and esters; particularly caffeic acid phenethyl ester (CAPE)

Antimicrobial
It has antibacterial activity against Gram (+) and Gram (-) germs, including Staphylococcus aureus, Pseudomonas aeruginosa and Streptococcus hemolyticus, as well as antimycotic activity against Candida albicans and antiviral against Herpes and Poliovirus. Propolis mechanism of action against infections is multiple: antibacterial, by increasing permeability on bacterial membranes with loss of ions and nutrients, reducing germ viability; antipathogen inhibiting virulence and resistance factors of bacteria, like biofilm formation and production of enzymes related to with hosts tissue damage.

Healing
Topical Propolis promotes keratinocyte proliferation, stimulating granulation tissue formation and facilitating autolytic debridement, which speeds up epithelial reconstruction process and early wound closure.

Anti-inflammatory
Propolis has significant anti-inflammatory action by reducing production of several inflammatory mediators considered pathogenic factors of rheumatic diseases, arteriosclerosis and cancer; linked to its capability to inhibit kappa B nuclear transcription factor, master key to genetic regulation of immune inflammatory processes. Unlike synthetic antinflammatories which only reduce prostaglandin E2, it also reduces leukotrienes, proinflammatory cytokines and several enzymes responsible for generating oxygen reactive species (free radicals).

Immunomodulator
Propolis promotes a regulated immune system balance. Acts as immunological adjuvant, intensifying acquired immune response dependent on antigens and significantly reducing innate immune response mediators like interleukin 1-β, 6 and 8 and tumor necrosis factor α (proinflammatory cytokines). It also prevents degranulation of mast cells responsible for allergic reactions such as rhinitis and asthma.

Antioxidant
Uruguayan Propolis antioxidant properties are very high due to its elevated content of polyphenols, inhibiting proinflammatory enzymes responsible for generating large quantities of oxygen reactive species during inflammatory process. This mechanism protects cell lipids and structural proteins from damage produced by oxygen stress.

PROPÓLEO-D DRESSING

Healing. Antimicrobial. Anti-inflammatory

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PROPÓLEO-D CREAM

For deep wet wounds

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PROPÓLEO-D LOTION

Hydrosoluble base formula

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PROPÓLEO-D POWDER

Enhances formation of scar tissue on wet wounds

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PROPÓLEO-D ADHESIVE SOLUTION

Forms an homogeneous adherent film

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PROPÓLEO-D OINTMENT

For dry superficial lesions

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PROPOL-Z POWDER

Speeds scar tissue formation in all kind of wounds

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